Our laboratory studies the genetic basis of adaptation and speciation using genomic analyses and field-based studies in the genus Aquilegia (Columbines).
Macroevolutionists study the processes that cause the origination and extinction of species, genes and functionally important traits - and the evolutionary patterns that result from these processes. Macroevolutionary study involves understanding the environmental factors and evolutionary innovations that influence speciation, diversification and extinction; timing and sequences of trait evolution; convergent evolution; and the correlated evolution of multiple traits. To accomplish these studies macroevolutionists utilize historical scientific methods, including tools from phylogenetics and paleontology.
Our lab addresses the question of how complex traits originate during evolution. We primarily study invertebrate visual systems and eyes, addressing questions like, when did a particular phenotype evolve? When did the components of that phenotype evolve? Where did those components come from? What evolutionary processes and mechanisms were involved?
Molecular and genetic control of development in the nematode C. elegans; regulation of programmed cell death; mechanisms of tumorigenesis.